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Beyond H. pylori and NSAIDs: Surprising Risk Factors for Peptic Ulcers
Published: May 13, 2024
While H. pylori bacteria and NSAID use are the most common causes of peptic ulcers, they're not the only risk factors. Understanding these lesser-known contributors can help you better protect your digestive health.
Lifestyle Factors That Increase Ulcer Risk
Smoking is a significant risk factor for peptic ulcers, as it increases stomach acid production and weakens the protective stomach lining. Excessive alcohol consumption can also irritate and erode your stomach lining. Chronic stress, while not a direct cause, can make you more susceptible to ulcers by affecting your immune system and increasing stomach acid production.
Medical Conditions Linked to Ulcers
Certain medical conditions can increase your risk of developing peptic ulcers. Zollinger-Ellison syndrome, a rare condition that causes tumors in the pancreas or duodenum, leads to excess stomach acid production. Crohn's disease, an inflammatory bowel condition, can also increase ulcer risk. Some studies suggest that people with blood type O may be more susceptible to H. pylori-related ulcers.
Surprising Medications That May Contribute
While NSAIDs are well-known ulcer culprits, other medications can also increase risk. These include some osteoporosis drugs called bisphosphonates, certain antibiotics, and even some antidepressants known as SSRIs. Always discuss potential side effects of your medications with your healthcare provider.
Frequently Asked Questions
Spicy foods don't cause ulcers, but may aggravate existing ones.
While stress can contribute, it's rarely the sole cause of peptic ulcers.
There may be a genetic component, but lifestyle factors play a larger role.
Knowledge is Power
By understanding all potential risk factors, you can take steps to reduce your chances of developing peptic ulcers.
References
- Li LF, et al. Cigarette smoking and gastrointestinal diseases: the causal relationship and underlying molecular mechanisms (review). Int J Mol Med 2014; 34:372.
- Chung CS, et al. A systematic approach for the diagnosis and treatment of idiopathic peptic ulcers. Korean J Intern Med 2015; 30:559.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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