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Contents
  • Commonly Used Antihistamines
  • Role of Antidepressants
  • Opioid Receptor Antagonists

Can These Medications Soothe Your Itch? Exploring Antipruritic Drugs

Can These Medications Soothe Your Itch? Exploring Antipruritic Drugs

The Big Picture

When itching becomes unbearable, medications might offer the relief you need. Discover which drugs can help.
Contents
  • Commonly Used Antihistamines
  • Role of Antidepressants
  • Opioid Receptor Antagonists

Commonly Used Antihistamines

Antihistamines are often the first choice for treating itchiness. They help block the action of histamine, a chemical in your body that causes itching. Common options include hydroxyzine and diphenhydramine, which work well for nighttime use due to their sedative effects.

Role of Antidepressants

Antidepressants can also be effective against chronic itching. These drugs, such as mirtazapine, act on serotonin and other chemicals that influence itching. They are particularly beneficial for itch linked to conditions like chronic kidney disease or liver problems.
Medications used to relieve itching, including antihistamines like hydroxyzine and diphenhydramine, and antidepressants such as mirtazapine.

Opioid Receptor Antagonists

For severe itching, opioid receptor antagonists like naltrexone might be prescribed. These medications modify how your brain processes itch signals, offering relief when other treatments fail. They are especially useful for itch associated with liver or kidney issues.

FAQs

How do antihistamines help with itch?

They block histamine, reducing itching and promoting sleep.

Can antidepressants relieve itching?

Yes, they can be effective for chronic itching conditions.

What are opioid receptor antagonists?

Drugs that modify brain signals to relieve severe itching.

Wrapping Up

Medications can offer significant relief from generalized pruritus, but consult a doctor for the best option.
Discuss with Doctronic which medications might work best for your itching.
Additional References
  1. Metz M, Ständer S. Chronic pruritus--pathogenesis, clinical aspects and treatment. J Eur Acad Dermatol Venereol 2010; 24:1249.
  2. Kouwenhoven TA, van de Kerkhof PCM, Kamsteeg M. Use of oral antidepressants in patients with chronic pruritus: A systematic review. J Am Acad Dermatol 2017; 77:1068.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic.