Decoding the Symptoms of Hyperparathyroidism
Published: May 03, 2024
Hyperparathyroidism symptoms can be elusive, often mimicking other health issues. This guide helps you identify the key symptoms.
Contents
The Classic Symptoms
The classic saying 'bones, stones, abdominal moans, and psychic groans' encapsulates the primary symptoms of PHPT. This phrase refers to bone pain, kidney stones, digestive issues, and mood disturbances. These symptoms arise due to increased parathyroid hormone levels and associated high calcium, which affect various body systems.
Neuromuscular and Neuropsychiatric Symptoms
PHPT can lead to neuromuscular symptoms like weakness and muscle cramps, as well as neuropsychiatric issues such as depression and cognitive dysfunction. These symptoms are often subtle and may go unnoticed until they're linked to PHPT. Recognizing these signs early can be crucial for timely intervention.

Less Common Symptoms
While not as common, some individuals with PHPT may experience severe symptoms like bone cysts or nephrolithiasis due to prolonged hormone imbalance. These symptoms can be more prevalent in regions with vitamin D deficiency and require careful monitoring and management to prevent complications.
Frequently Asked Questions
Bone pain, kidney stones, digestive issues, and mood changes.
Yes, it can lead to depression and cognitive issues.
Yes, muscle cramps can occur due to PHPT.
Nephrolithiasis is the formation of kidney stones.
Wrapping Up
Being aware of PHPT symptoms can lead to earlier diagnosis and treatment.
References
- Bilezikian JP, Silverberg SJ. Clinical practice. Asymptomatic primary hyperparathyroidism. N Engl J Med 2004; 350:1746.
- Joborn C, Hetta J, Johansson H, et al. Psychiatric morbidity in primary hyperparathyroidism. World J Surg 1988; 12:476.
- Chiodini I, Cairoli E, Palmieri S, et al. Non classical complications of primary hyperparathyroidism. Best Pract Res Clin Endocrinol Metab 2018; 32:805.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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