Diagnosing Antiphospholipid Syndrome: Tests You Need to Know
Published: Feb 19, 2024
Identifying Antiphospholipid Syndrome (APS) involves specific tests that detect the presence of antibodies in the blood. Understanding these tests can help you anticipate the diagnostic process.
Contents
Key Blood Tests
The diagnosis of APS primarily relies on blood tests identifying specific antibodies. These include the anticardiolipin antibodies, lupus anticoagulant, and anti-beta2 glycoprotein I antibodies. Positive results on these tests, along with clinical symptoms, confirm APS.
Interpreting Test Results
Antibody levels can vary, and it's crucial to interpret them in conjunction with symptoms. High antibody levels increase the likelihood of APS, but repeated testing may be necessary for accurate diagnosis. Consulting with a healthcare provider is vital for understanding test outcomes.

The Role of Imaging
In some cases, imaging tests like MRI may be used to assess the impact of APS on organs such as the brain and heart. These tests help in evaluating the extent of damage caused by blood clots. Imaging results, combined with blood tests, provide a comprehensive view of the condition.
Frequently Asked Questions
Blood tests for specific antibodies are used.
Not always; repeated tests may be needed.
Yes, it assesses the impact of blood clots.
The Bottom Line
Understanding APS tests aids in timely diagnosis and management.
References
- Pengo V, Biasiolo A, Pegoraro C, et al. Antibody profiles for the diagnosis of antiphospholipid syndrome. Thromb Haemost 2005; 93:1147.
- Ruffatti A, Tonello M, Del Ross T, et al. Antibody profile and clinical course in primary antiphospholipid syndrome with pregnancy morbidity. Thromb Haemost 2006; 96:337.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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