Guillain-Barré Syndrome: What You Need to Know About This Rare Nerve Disorder
Published: Jun 08, 2024
Guillain-Barré syndrome (GBS) is a rare autoimmune disorder that attacks the nerves, causing muscle weakness and sometimes paralysis. While it can be scary, most people recover with proper treatment.
Contents
What Causes GBS?
The exact cause of GBS isn't known, but it often occurs after an infection. Your immune system, which normally fights off invaders, mistakenly attacks your nerves. This is like friendly fire in your body - your defense system accidentally hurts your own troops. Common triggers include gastrointestinal or respiratory infections, but sometimes there's no clear cause.
Recognizing the Symptoms
GBS typically starts with weakness and tingling in your legs and feet. These sensations can quickly spread upwards, potentially affecting your whole body. In severe cases, muscles controlling breathing can be impacted, leading to breathing difficulties. Some people also experience severe pain. The symptoms usually peak within a few weeks.

Diagnosis and Treatment
Doctors diagnose GBS through a combination of symptoms, physical exam, and tests like spinal fluid analysis and nerve conduction studies. The main treatments are plasma exchange (which filters harmful antibodies from your blood) and intravenous immunoglobulin therapy (which introduces healthy antibodies to block the harmful ones). Most people start improving within weeks and recover fully, though some may have lasting effects.
Recovery and Long-term Outlook
Recovery from GBS can take months or even years. Most people regain full strength and sensation, but some may have lingering weakness, numbness, or fatigue. Physical therapy plays a crucial role in recovery. While relapses are rare, it's important to monitor for any returning symptoms.
Frequently Asked Questions
GBS affects about 1 in 100,000 people annually.
There's no known way to prevent GBS.
No, GBS isn't contagious.
Yes, but it's more common in adults and older people.
It can be, but most people recover with proper treatment.
Key Takeaways
While GBS is a serious condition, most people recover with proper medical care and support.
References
- Hughes RA, et al. Lancet Neurol. 2014;13(1):70-82.
- Willison HJ, et al. Lancet. 2016;388(10045):717-727.
- van den Berg B, et al. Nat Rev Neurol. 2014;10(8):469-482.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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