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Managing Thalassemia: What Treatments Are Available?
Published: Nov 03, 2023
Managing thalassemia involves various treatments to control symptoms and improve quality of life. Discover the available options and how they work.
Blood Transfusions
Regular blood transfusions are a cornerstone treatment for severe thalassemia, providing healthy red blood cells to improve anemia. They help manage symptoms like fatigue and organ damage caused by low hemoglobin levels. However, they require careful monitoring to avoid iron overload.
Iron Chelation Therapy
Iron chelation therapy removes excess iron from the body, a common complication of frequent blood transfusions. Medications like deferoxamine help prevent organ damage due to iron buildup. It's a crucial part of thalassemia management to avoid complications.
Stem Cell Transplantation
For some, hematopoietic stem cell transplantation offers a potential cure by replacing defective blood-forming cells. This treatment is considered for severe cases and involves finding a compatible donor. While risky, it can lead to long-term remission of thalassemia.
Frequently Asked Questions
Regular blood transfusions are the primary treatment.
To remove excess iron from frequent transfusions.
Stem cell transplantation offers a potential cure for severe cases.
It involves risks such as rejection and infections.
Treatment Takeaway
Effective management of thalassemia requires a combination of treatments tailored to each individual.
References
- Forget BG. Thalassemia syndromes. In: Hematology: Basic Principles and Practice, 3rd ed, Hoffman R, Benz EJ Jr, Shattil SJ, et al. (Eds), Churchill Livingstone, New York 2000. p.485.
- Olivieri NF. The beta-thalassemias. N Engl J Med 1999; 341:99.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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