The Secret to Strong Bones: Managing Glucocorticoid Side Effects
Published: May 31, 2024
Managing the bone-weakening side effects of glucocorticoids is crucial for maintaining strong bones. Discover the therapies that can help counteract these effects.
Contents
The Impact of Glucocorticoids on Bone Health
Glucocorticoids can lead to increased bone resorption and decreased bone formation, causing bones to weaken over time. These medications also interfere with calcium absorption, contributing to further bone loss.
Therapies to Strengthen Bones
Therapies like bisphosphonates can help prevent bone loss in those on glucocorticoid therapy. These medications work by slowing down the cells that break down bone, helping maintain bone strength and reducing fracture risk.

Supplementing with Calcium and Vitamin D
Calcium and vitamin D supplements are often recommended alongside glucocorticoid therapy. These supplements help counteract the decreased absorption caused by glucocorticoids, supporting overall bone health.
Frequently Asked Questions
They increase bone resorption and decrease formation, weakening bones.
Bisphosphonates are effective in slowing bone loss.
They help support bone health by counteracting glucocorticoid effects.
Key Takeaways
Effective therapies can help manage glucocorticoid side effects and maintain strong bones.
References
- Cohen S, Levy RM, Keller M, et al. Risedronate therapy prevents corticosteroid-induced bone loss: a twelve-month, multicenter, randomized, double-blind, placebo-controlled, parallel-group study. Arthritis Rheum 1999; 42:2309.
- Adami G, Saag KG. Glucocorticoid-induced osteoporosis: 2019 concise clinical review. Osteoporos Int 2019; 30:1145.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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