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What is Antiphospholipid Syndrome and Why You Should Care?
Published: Sep 14, 2023
Antiphospholipid Syndrome (APS) is a condition that causes your immune system to attack essential proteins in your blood, leading to blood clots and pregnancy complications. Knowing about APS can help you recognize its symptoms and seek timely medical advice.
What Causes APS?
APS is primarily an autoimmune disorder where the body's defense system mistakenly targets phospholipid-binding proteins. These proteins are crucial for blood clot regulation, and their disruption can result in excessive clotting in veins and arteries. APS may occur on its own or alongside other autoimmune diseases like systemic lupus erythematosus (SLE).
Recognizing the Symptoms
The primary signs of APS include deep vein thrombosis, stroke, and pregnancy-related issues like recurrent miscarriages. Secondary symptoms may involve skin conditions such as livedo reticularis, cardiac valve disease, and neurological issues like transient ischemic attacks. Early detection of these signs is crucial for preventing severe complications.
APS and Pregnancy
Pregnancy complications are a hallmark of APS, including recurrent miscarriages and severe preeclampsia. Women with APS may experience fetal loss either before 10 weeks or after due to placenta-related issues. Timely management and monitoring of pregnancy in women with APS are vital to ensure the safety of both mother and child.
Frequently Asked Questions
APS is an autoimmune disorder causing blood clots and pregnancy complications.
It can cause recurrent miscarriages and severe preeclampsia.
Symptoms include deep vein thrombosis, stroke, and skin conditions.
Yes, it often occurs with lupus.
Key Takeaways
Understanding APS is crucial for early diagnosis and effective management of the condition.
References
- Miyakis S, Lockshin MD, Atsumi T, et al. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost 2006; 4:295.
- Andreoli L, Chighizola CB, Banzato A, et al. Estimated frequency of antiphospholipid antibodies in patients with pregnancy morbidity, stroke, myocardial infarction, and deep vein thrombosis: a critical review of the literature. Arthritis Care Res (Hoboken) 2013; 65:1869.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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