What You Need to Know About Polycythemia Vera: A Sneak Peek Into the Blood Disorder
What You Need to Know About Polycythemia Vera: A Sneak Peek Into the Blood Disorder
The Big Picture
Polycythemia vera (PV) is a rare blood disorder that makes your body produce too many red blood cells. This article explores what PV is, its symptoms, and how it's diagnosed.
Contents
Understanding Polycythemia Vera
Polycythemia vera is a type of blood cancer where the bone marrow makes too many red blood cells. This overproduction can thicken the blood, slowing its flow and leading to complications like blood clots. It's part of a group of conditions called myeloproliferative neoplasms, which involve abnormal growth of blood cells.
Symptoms to Watch For
Many people with PV don't notice symptoms at first, and it's often found during routine blood tests. Some symptoms include headaches, dizziness, and a red or flushed face. Other signs can be itching, especially after a warm bath, and a feeling of fullness on the left side of the abdomen due to an enlarged spleen.
How Is Polycythemia Vera Diagnosed?
Diagnosis of PV usually begins with a blood test showing high levels of red blood cells. Doctors may also check for a specific mutation called JAK2, which is present in most cases of PV. Further tests, like a bone marrow biopsy, may be done to confirm the diagnosis and rule out other conditions.
FAQs
What is polycythemia vera?
Polycythemia vera is a blood disorder where the body makes too many red blood cells.
What are common symptoms of PV?
Common symptoms include headaches, dizziness, itching, and a flushed face.
How is PV diagnosed?
PV is diagnosed through blood tests showing high red blood cells and checking for JAK2 mutation.
Is polycythemia vera common?
PV is a rare condition with an incidence of about 1.9 per 100,000 people per year.
Key Takeaways
Understanding PV's symptoms and diagnosis is crucial for early detection and management.
Additional References
- Passamonti F, Malabarba L, Orlandi E, et al. Polycythemia vera in young patients: a study on the long-term risk of thrombosis, myelofibrosis and leukemia. Haematologica 2003; 88:13.
- Teofili L, Giona F, Martini M, et al. Markers of myeloproliferative diseases in childhood polycythemia vera and essential thrombocythemia. J Clin Oncol 2007; 25:1048.
- Tefferi A, Rumi E, Finazzi G, et al. Survival and prognosis among 1545 patients with contemporary polycythemia vera: an international study. Leukemia 2013; 27:1874.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic.