Blood tests are usually the first step in diagnosing acute pancreatitis. Doctors look for elevated levels of two enzymes: amylase and lipase. These enzymes are normally produced by the pancreas but leak into the bloodstream when the pancreas is inflamed. Lipase is considered more accurate and stays elevated longer than amylase. If these enzymes are more than three times the normal limit, it strongly suggests pancreatitis.

If blood tests are inconclusive or doctors want to check for complications, they may order imaging tests. A CT scan is often the go-to choice. It can show an enlarged, inflamed pancreas and detect any complications like fluid collections or necrosis (tissue death). In some cases, an MRI might be used instead, especially if there's concern about the bile ducts or in patients with kidney problems.

Doctors may also order other blood tests to check for underlying causes or assess the severity of pancreatitis. These might include liver function tests, triglyceride levels, and calcium levels. In some cases, an ultrasound might be done to look for gallstones, a common cause of acute pancreatitis.

While the diagnostic process might seem complex, these tests help doctors accurately diagnose and treat acute pancreatitis.