Step-by-Step Guide: Preparing for a Dexamethasone Suppression Test
Published: Sep 26, 2024
Preparing for a dexamethasone suppression test (DST) is key for accurate results. This guide walks you through the steps to ensure you're ready for the test.
Contents
Before the Test
Consult your doctor about any medications you're taking, as some can affect the test results. Avoid alcohol and caffeine, as they may interfere with cortisol levels. Ensure you get a good night's sleep before the test for the most accurate results.
The Night of the Test
You'll take a dose of dexamethasone, usually 1 mg, around 11 PM. Make sure to follow the dosing instructions carefully. This is crucial because the timing and dosage affect how well the test can measure cortisol suppression.

What to Expect After
The morning after taking dexamethasone, you'll have a blood sample taken, typically around 8 AM. This sample will be used to measure cortisol levels and determine how well your body suppressed cortisol production. Results will guide further diagnostic steps if needed.
Frequently Asked Questions
It's a test to measure cortisol levels after taking dexamethasone.
Avoid certain meds, alcohol, caffeine, and ensure adequate sleep.
The test usually involves taking dexamethasone at night and a blood test in the morning.
Proper timing ensures accurate cortisol suppression measurement.
Next Steps
Proper preparation for a DST can lead to accurate and useful results in diagnosing cortisol imbalances.
References
- Cronin C, Igoe D, Duffy MJ, et al. The overnight dexamethasone test is a worthwhile screening procedure. Clin Endocrinol (Oxf) 1990; 33:27.
- Findling JW, Raff H. Recognition of Nonneoplastic Hypercortisolism in the Evaluation of Patients With Cushing Syndrome. J Endocr Soc 2023; 7:bvad087.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
AI Doctor Visit Required
Appointments available 24/7
15-min consultation. No hidden costs.
AI Doctor Visit Required
For safety reasons we have been forced to end this consultation.
If you believe this is a medical emergency please call 911 or your local emergency services immediately.
If you are experiencing emotional distress, please call the the Suicide & Crisis Lifeline at 988 or your local crisis services immediately.
Contact us
You can also email us at help@doctronic.ai
We aim to reply within 5-7 days
How likely are you to recommend Doctronic to friends or family?