What's Behind the Lab Tests for Jaundice?
What's Behind the Lab Tests for Jaundice?
Why It Matters
Understanding lab tests for jaundice can demystify this condition and aid in early detection of underlying health issues.
Contents
- Initial Lab Tests
- Patterns of Injury
- Advanced Imaging
Initial Lab Tests
The first step involves measuring serum bilirubin levels, both total and unconjugated, as well as aminotransferases and alkaline phosphatase. These tests help determine if the liver or bile ducts are involved. Abnormal results can indicate jaundice and suggest further testing is needed.
Patterns of Injury
Lab tests can reveal patterns like cholestatic or hepatocellular injury. Cholestatic patterns show high alkaline phosphatase levels, while hepatocellular patterns show high aminotransferase levels. These patterns help pinpoint the problem's source.
Advanced Imaging
If lab tests suggest bile duct issues, imaging such as ultrasound, MRCP, or EUS may be used. These tests visualize the bile ducts to check for blockages or other abnormalities. Confirming the presence of obstruction guides treatment options.
FAQs
What are the key lab tests for jaundice?
Key tests include serum bilirubin, aminotransferases, and alkaline phosphatase levels.
What does a cholestatic pattern mean?
It indicates elevated alkaline phosphatase levels, suggesting bile duct obstruction or liver issues.
Why might advanced imaging be needed?
Imaging helps confirm bile duct blockages when lab tests indicate potential obstruction.
Wrapping Up
Lab tests are vital tools in assessing jaundice and determining the appropriate course of action.
Additional References
- Saini S. Imaging of the hepatobiliary tract. N Engl J Med 1997; 336:1889.
- Newsome PN, Cramb R, Davison SM, et al. Guidelines on the management of abnormal liver blood tests. Gut 2018; 67:6.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic.