What's the Mystery Behind Primary Amenorrhea?
What's the Mystery Behind Primary Amenorrhea?
The Big Picture
Primary amenorrhea, the absence of menstruation by age 15, can be puzzling. This article explores common causes and what they mean for young women.
Contents
Understanding Primary Amenorrhea
Primary amenorrhea is when a girl hasn't started menstruating by age 15. It's important to evaluate this condition to find the underlying cause. It can result from issues in the hypothalamus, pituitary, ovaries, uterus, or vagina.
Genetic and Anatomical Causes
A significant cause of primary amenorrhea is genetic or anatomical abnormalities. Gonadal dysgenesis, including Turner syndrome, is the most common, affecting 43% of cases. Other causes can include Müllerian agenesis and congenital defects in reproductive organs.
Hormonal Factors and Delays
Hormonal issues can also lead to primary amenorrhea. Conditions like functional hypothalamic amenorrhea, where stress or weight loss affects hormone release, are common. Some cases involve delayed puberty, seen more often in boys but can occur in girls.
FAQs
What is primary amenorrhea?
It's the absence of menstruation by age 15.
What causes primary amenorrhea?
Genetic issues or hormonal imbalances are common causes.
How common is Turner syndrome in amenorrhea?
Turner syndrome affects 43% of primary amenorrhea cases.
Can stress cause amenorrhea?
Yes, stress can disrupt hormone release leading to amenorrhea.
Is delayed puberty a cause?
Yes, it can occur but is less common in females.
The Bottom Line
Understanding the causes of primary amenorrhea is crucial for proper diagnosis and treatment.
Additional References
- Practice Committee of the American Society for Reproductive Medicine. Fertil Steril 2006; 86:S148.
- Reindollar RH, Byrd JR, McDonough PG. Am J Obstet Gynecol 1981; 140:371.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic.