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Preventing the Unwanted Side Effects of Glucocorticoids
Published: Jul 24, 2024
Glucocorticoids are helpful in many treatments, but their side effects can be daunting. Learn how to prevent these adverse effects with proactive measures.
Vaccinations and Infections
Patients on long-term glucocorticoid therapy should receive appropriate vaccinations to prevent infections. Glucocorticoids can suppress the immune system, making patients more susceptible to infections. Preventive measures like vaccinations before starting therapy can reduce this risk significantly.
Bone Health Maintenance
To prevent bone-related side effects, patients should ensure adequate intake of calcium and vitamin D. Weight-bearing exercises are also vital for maintaining bone density. Regular bone density screenings can help detect early signs of osteoporosis.
Monitoring Blood Sugar Levels
Patients should monitor their blood sugar levels regularly, especially if they have a history of diabetes. Glucocorticoids can cause hyperglycemia, so dietary adjustments and regular check-ups are essential. Early detection of blood sugar changes can prevent the onset of diabetes.
Skin Protection Strategies
Skin thinning and bruising are common with glucocorticoid use. Patients should protect their skin by using sunscreen and moisturizers. Avoiding excessive sun exposure and being gentle with the skin can help reduce these side effects.
Frequently Asked Questions
Appropriate vaccinations can reduce infection risk.
Calcium, vitamin D, and exercise support bone health.
Glucocorticoids can cause hyperglycemia, leading to diabetes.
Use sunscreen and moisturizers to protect the skin.
Yes, they help detect early signs of osteoporosis.
Stay Proactive
Proactive prevention is key to minimizing glucocorticoid side effects.
References
- Fardet L, Petersen I, Nazareth I. Suicidal behavior and severe neuropsychiatric disorders following glucocorticoid therapy in primary care. Am J Psychiatry 2012; 169:491.
- Messer J, Reitman D, Sacks HS, et al. Association of adrenocorticosteroid therapy and peptic-ulcer disease. N Engl J Med 1983; 309:21.
- Pernicova I, Kelly S, Ajodha S, et al. Metformin to reduce metabolic complications and inflammation in patients on systemic glucocorticoid therapy: a randomised, double-blind, placebo-controlled, proof-of-concept, phase 2 trial. Lancet Diabetes Endocrinol 2020; 8:278.
- Brogan P, Naden R, Ardoin SP, et al. The pediatric glucocorticoid toxicity index. Semin Arthritis Rheum 2022; 56:152068.
- Stone JH, McDowell PJ, Jayne DRW, et al. The glucocorticoid toxicity index: Measuring change in glucocorticoid toxicity over time. Semin Arthritis Rheum 2022; 55:152010.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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