Therapies for Hypercalcemia: What Works Best?
Therapies for Hypercalcemia: What Works Best?
Why It Matters
Choosing the right therapy for hypercalcemia is key to effective management and long-term control.
Contents
- Immediate Therapies
- Long-Term Management
- Alternative Options
Immediate Therapies
For immediate management of severe hypercalcemia, intravenous saline and calcitonin are often used. These therapies work quickly to reduce calcium levels and provide initial relief from symptoms. They are usually combined with other treatments for sustained control.
Long-Term Management
Long-term control of hypercalcemia often involves bisphosphonates, which help reduce bone resorption. These medications are effective for managing chronic cases and preventing recurrence. In some cases, denosumab may be used, especially if bisphosphonates are not suitable.
Alternative Options
In patients with kidney issues or those who don't respond well to standard treatments, dialysis may be considered. This approach is usually a last resort but can be effective in stabilizing calcium levels in severe cases.
FAQs
What are immediate therapies?
Intravenous saline and calcitonin are used for quick relief.
How is long-term control achieved?
Bisphosphonates are commonly used for long-term management.
What if standard treatments don't work?
Dialysis might be considered as a last resort.
Wrapping Up
Effective therapy for hypercalcemia depends on the severity and underlying cause.
Additional References
- Gucalp R, Theriault R, Gill I, et al. Treatment of cancer-associated hypercalcemia. Arch Intern Med 1994; 154:1935.
- Major P, Lortholary A, Hon J, et al. Zoledronic acid is superior to pamidronate in the treatment of hypercalcemia of malignancy. J Clin Oncol 2001; 19:558.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic.