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Which Medications Can Help Lower Triglycerides?
Published: Oct 16, 2023
Medications play a significant role in managing hypertriglyceridemia, especially when lifestyle changes aren't enough. This article highlights key drugs used in treatment.
Statins and Their Benefits
Statins are primarily used to lower LDL cholesterol and reduce cardiovascular risk. However, they also have mild to moderate triglyceride-lowering effects. High-intensity statins like atorvastatin and rosuvastatin can reduce triglycerides by up to 44%, which may help lower the risk of pancreatitis.
Marine Omega-3 Fatty Acids
Marine omega-3 fatty acids, such as icosapent ethyl, are effective in lowering triglyceride levels. They can reduce triglyceride levels by 20 to 50% depending on the dose and baseline triglyceride levels. They are often recommended for patients at high cardiovascular risk.
The Role of Fibrates
Fibrates, like fenofibrate and gemfibrozil, are potent triglyceride-lowering agents. They can reduce triglyceride levels by up to 70% and are often used when triglyceride levels remain high despite other treatments. However, they may interact with statins and require careful monitoring.
Frequently Asked Questions
Yes, high-intensity statins can significantly lower triglyceride levels.
They are fats found in fish oil that help reduce triglyceride levels.
Fibrates can lower triglycerides by up to 70%, making them very effective.
Yes, there can be side effects and drug interactions, especially with fibrates.
Key Takeaways
Medications like statins, omega-3s, and fibrates are vital in managing high triglyceride levels.
References
- Bakker-Arkema RG, Davidson MH, Goldstein RJ, et al. Efficacy and safety of a new HMG-CoA reductase inhibitor, atorvastatin, in patients with hypertriglyceridemia. JAMA 1996; 275:128.
- Bhatt DL, Steg PG, Miller M, et al. Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia. N Engl J Med 2019; 380:11.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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